In order to evaluate the anti-inflammatory effect of a therapeutic toothpaste containing TNA, ALCA, Vit-E, and MFP on gingivitis, the authors had examined the periodontal status of 240 female junior technical college students aged from 19 to 20, and divided into two groups, 120 students in one control group were given with cosmetic toothpastes, 120 students in the other experimental group with therapeutic toothpaste containing TNA, ALCA, Vit-E, and MFP. At the same time, all students were given with straight handled medium bristled toothbrush and directed to brush teeth with toothpaste and toothbrush offered.
Thereafter, the gingival tissues were repeatedly examined in the 20th day, 40th day, 80th day, and 160th day. From the collected data, the percentages of gingival units, where the inflammatory signs in the initial periodontal examination disappeared, to the gingival units with the inflammatory signs in the initial periodontal examination and the relative potency were calculated and discussed.
The obtained results were as follows:
1. The relative potency of therapeutic toothpaste versus cosmetic toothpaste was 1.11:1.
2. It is recommended that the dentifrice with more potent therapeutic effect should be developed.
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